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Human CD133(+) BMDSCs were obtained from patients undergoing autologous cell therapy in refractory AS and endometrial atrophy, labeled with SPIOs and injected either intrauterinely (n = 5) or systemically through the tail vein (n = 5) in the animal model.Īccumulation of collagen and glycosaminoglycan deposits detected by trichrome staining.
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Nonobese diabetic mice (strain code 394 NOD.CB17- Prkdc(scid)/NcrCrl) in which AS was induced according to a published protocol. To investigate the engraftment and proliferation of superparamagnetic iron oxide nanoparticles (SPIOs)-labeled human CD133(+) bone marrow-derived stem cells (BMDSCs) in an animal model of Asherman syndrome (AS). 7 Fundación Instituto Valenciano de Infertilidad (FIVI), Department of Obstetrics & Gynecology, School of Medicine, Valencia University and Instituto Universitario IVI/INCLIVA, Valencia, Spain School of Medicine, Valencia University, Valencia, Spain Department of Obstetrics & Gynecology, Stanford University School of Medicine, Stanford University, Stanford, California.
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